brain

Transport of amino acids (including tyrosine and phenylalanine) from blood to brain

Published: September 2017 in Plos One
Article: Transport of amino acids (including tyrosine and phenylalanine) from blood to brain
Authors: WG van Ginkel, D van Vliet, JGM Burgerhof, P de Blaauw, ME Rubio-Gozalbo, MR Heiner-Fokkema, FJ van Spronsen
Contact: Wiggert van Ginkel
Link to article: ncbi.nlm.nih.gov

It is currently unknown why the IQ of Tyrosinemia type 1 patients is lower when compared to healthy control participants. Som theories exist. It has been hypothesized that increased tyrosine concentrations and/or decreased phenylalanine concentrations could lead to changes in brain function.

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