liver

Liver cancer in a Tyrosinemia type 1 patient without increase in blood AFP concentrations

Publication: March 2015 in Pediatrics
Article: Liver cancer in a Tyrosinemia type 1 patient without increase in blood AFP concentrations.
Authors: WG van Ginkel, AS Gouw, EJ van der Jagt, KP de Jong, HJ Verkade, FJ van Spronsen
Contact: Wiggert van Ginkel
Link to article: Pediatrics

Liver cancer was very common before Tyrosinemia type 1 patients were treated with the drug NTBC. The risk of liver cancer formation decreased tremendously after the introduction of NTBC, especially if NTBC treatment was initiated early and if alfa-1-foetoproteine (or AFP in short) concentrations quickly decrease to normal concentrations.

Continue reading this published study about liver cancer in a Tyrosinemia type 1 patient without increase in blood AFP concentrations

 


 

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